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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name hsa-miR-498
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB cell line Y79; RPE cell line ARPE-19
Methods qRT-PCR, transfection, cell apoptosis analysis, luciferase reporter assay, Western blot, MTT assay
Expression pattern up-regulated
Functional description miR-498 promotes cell proliferation and inhibits cell apoptosis in Rb by directly targeting CCPG1.
PubMed ID 29247256
Year 2018
Title miR-498 promotes cell proliferation and inhibits cell apoptosis in retinoblastoma by directly targeting CCPG1.
Drug-related ncRNA NO

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